Trade name: Lenvima
Lenvatinib is the generic for the trade name drug Lenvima. In
some cases, health care professionals may use the trade name Lenvima
when referring to the generic drug name lenvatinib.
Lenvatinib is a targeted therapy. It is an oral
receptor tyrosine kinase inhibitor
What this drug is used for:
- For the treatment of patients with locally recurrent or
metastatic, progressive, radioactive iodine-refractory
differentiated thyroid cancer.
Note: If a drug has been approved for one use, physicians may elect to
use this same drug for other problems if they believe it may be helpful.
How this drug is given:
- Lenvatinib is a pill, taken by mouth, once daily. It can be taken
with or without food.
- Take lenvatinib exactly as prescribed.
- Swallow lenvatinib capsules whole. Do not crush, dissolve or open
- Do not change your dose or stop lenvatinib unless your health
care provider tells you to.
- If you miss a dose, take it as soon as you remember. If your next
dose is within 12 hours, skip the missed dose and take the next dose
at your regular time.
- Do not take more than 1 dose of lenvatinib at one time. Call your
health care provider right away if you take too much.
- The amount of lenvatinib that you will receive depends on many
factors, your general health or other health problems, and the type
of cancer or condition being treated.
- Dose modifications are often made so it is important to let your
healthcare provider know of any side effects.
Important things to remember about the side effects of lenvatinib:
The following side effects are common (occurring in greater than
30%) for patients taking lenvatinib:
- Most people do not experience all of the side effects listed.
- Side effects are often predictable in terms of their onset and
- There are many options to help minimize or prevent side effects.
- There is no relationship between the presence or severity of side
effects and the effectiveness of the medication.
- High blood pressure
- Joint/muscle aches
- Decreased appetite
- Weight loss
- Stomatitis (mouth sores)
- Proteinuria (protein in the urine)
- Palmar-plantar erythrodysesthesia (hand-foot syndrome)
- Abdominal pain
- Dysphonia (difficulty speaking)