Ixazomib
Trade name: Ninlarox™
Ixazomib is the generic name for the trade name drug Ninlaro. In some cases, health care professional may use the trade name Ninlaro when referring to the generic drug name, ixazomib.

Drug type: Ixazomib is an anti-cancer ("antineoplastic" or "cytotoxic") chemotherapy drug. This medication is classified as a "proteasome inhibitor." (For more detail, see "How Ixazomib Works" below)

What Ixazomib Is Used For :
  • Multiple myeloma, Ixazomib is used in combination with lenalidomide and dexamethasone in patients who have received at least one prior therapy

Note: If a drug has been approved for one use, physicians may elect to use this same drug for other problems or in different combinations if they believe it may be helpful.

How Ixazomib Is Given :
  • Ixazomib is a capsule taken once a week for 3 out of 4 weeks (Days 1, 8, 15 of a 28 day cycle).
  • Ixazomib should be taken on the same day of the week and at the same time of day.
  • Ixazomib should be taken on an empty stomach (1 hour before or two hours after a meal).
  • The capsule should be swallowed whole with a glass of water. Do not open the capsule, crush, chew or dissolve it.
  • If a dose is delayed or missed, take it only if the next schedule dose is at least 72 hours away. Do not take a missed dose within 3 days of the next scheduled dose. Do not double a dose to make up for a missed dose. If vomiting occurs, do not repeat the dose; resume dosing at the next scheduled dose.

The amount of ixazomib that you will receive depends on many factors, including your height and weight, your general health or other health problems (e.g. kidney, liver problems), and the type of cancer or condition you have. Your doctor will determine your exact dosage and schedule.